Role of partial protein unfolding in alcohol-induced protein aggregation
نویسندگان
چکیده
منابع مشابه
Role of partial protein unfolding in alcohol-induced protein aggregation.
Proteins aggregate in response to various stresses including changes in solvent conditions. Addition of alcohols has been recently shown to induce aggregation of disease-related as well as nondisease-related proteins. Here we probed the biophysical mechanisms underlying alcohol-induced protein aggregation, in particular the role of partial protein unfolding in aggregation. We have studied aggre...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Bioinformatics
سال: 2010
ISSN: 0887-3585,1097-0134
DOI: 10.1002/prot.22778